Browse treatments

…multi-omic understanding of its spatial architecture to improve therapeutic strategies. Spatial transcriptomics with the Xenium™ platform enables mapp…

…Background Chimeric antigen receptor T-cell (CAR-T) therapy and bispecific antibodies (BsAbs) represent two major advances …

…mally interact with and recognize their target is important for cellular immunotherapies. Tumor-specific but mildly-effective T-cells can confound this …

…Background Cancer immunotherapies have become an effective tool by manipulating cellular immune r…

…temic comorbidity and cellular-level damage.1 In the context of immune checkpoint inhibitor (ICI) therapy, smoking and smoking-associated mutational signatures have been…

…nd major pathologic responses in stage III melanoma compared to adjuvant therapy, establishing a new standard of care. 1 2 However, nearly half …

…stance of TIL clusters. In 6 responders and 3 non-responders to immune checkpoint blockade therapy for colorectal cancer, responders showed higher mean TIL densit…

…ionship of lymphocyte distribution with cell surface targets in immunotherapy, a standardized and reproducible analytical Methods is essentia…

… (MPR) in non-small cell lung cancer (NSCLC) patients receiving neoadjuvant chemotherapy combined with immune checkpoint inhibitors (ICIs).Methods Cases…

…idating the extensibility of model signatures in the context of immunotherapy treatment in hepatocellular carcinoma. This work highlights the Atlas’ ut…

… of the tumor microenvironment (TME) is essential for advancing immunotherapy in solid tumors. While spatial transcriptomics provides detaile…

…pectral imaging with the AstroPath platform informs efficacy of PD-1 blockade. Science. 2021;372:eaba2609.Shaban M, Bai Y, Qiu H, et al. MAPS…