… accuracy and consistency of TMB measurements, particularly for immunotherapy decision-making.Methods We analyzed 202 tumor samples from lung…
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Articles mentioning treatments
7,227 articles · page 491 of 603…imulates T cell activation has renewed interest as a target for cancer immunotherapy. However, its clinical efficacy is still limited without approp…
…ifferent mutational loci in the TERT promoter in the context of modern therapy, specifically in advanced and metastatic melanoma.Methods Using…
…rthermore, in CRPC patients who acquired AR mutations following androgen deprivation therapy (ADT) or novel hormonal agents (NHA), immune cell infiltration,…
…ally leading to better clinical outcomes and better response to immunotherapy. However, the causal factors underlying this difference between…
…sentation. While immune checkpoint blockade (ICB) combined with chemotherapy provides limited benefits, most patients do not achieve durable…
…ncies and select solid tumors, making it an emerging target for immunotherapy. However, comprehensive analyses comparing CD70 expression betw…
…licated in immune evasion, tumor progression, and resistance to checkpoint blockade. Several CD70-targeted therapies are under active clinical deve…
…s, revealing mechanistic insights with the potential to support cancer therapy development.Conclusions Our study highlights the power of the G…
…Background Neoadjuvant/perioperative chemoimmunotherapy is a standard of care for treating patients with resectable non…
…. high, p = .03). A greater proportion of patients who received pre-operative chemotherapy were found in TLS High compared to TLS Absent and Intermediate …
…small proportion of patients. Excitingly, ICI are now moving to first line therapy. To predict response and improve efficacy of ICIs, detailed ins…