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…s frequently receive lymphocyte-suppressive corticosteroids and chemoradiation, we asked whether a low pre-treatment absolute lymphocyte count…

…ld tumors, where conventional checkpoint inhibitors often fail. Chemotherapy, particularly agents like Docetaxel, can induce immunogenic cel…

…CC) remains a major cause of cancer-related mortality. Although immunotherapy has demonstrated efficacy in a subset of patients, outcomes var…

…etics in patients with HPV-associated malignancies treated with immunotherapy.3 We evaluated HPV16/18-ctDNA as a predictive biomarker of clin…

…iopsies were obtained from gastric cancer patients treated with first-line ICI-based chemotherapy (N=90) or chemotherapy alone (N=10). Based on progression-free …

…sponse (pCR) at the time of definitive surgery who had received chemotherapy along with Pembrolizumab as neoadjuvant settings. After the def…

…Background Cancer immunotherapy has evolved over decades into a frontline treatment for multipl…

… adenocarcinoma (LUAD) patients exhibit intrinsic resistance to neoadjuvant chemoimmunotherapy (N=816 trial cohort), underscoring an unmet need for mechanism-…

…Background Immune-checkpoint blockade therapies have revolutionized cancer treatment; however, such immunothera…

…dder cancer DC1/CD8+ T cell clustering is a key requirement for PD-1/PD-L1 blockade efficacy, and FGFR3 activation mediates resistance by disruptin…

…al analysis of a longitudinally sampled MM patient treated with ICB revealed distinct resistance clones associated with different m…

…ve tumor microenvironment (TME) that limit T-cell infiltration. Laser interstitial thermal therapy (LITT), a minimally invasive ablation technique, provides local…