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…nched two new PRO projects and held two exploratory meetings on immune resetting therapies that generated remarkable community engagement and led to the d…

…and disease subgroups hinder the development and application of targeted therapeutic approaches. Community-wide access to a longitudinal, highly curated, centr…

…ents received antimalarials and 95.8% systemic corticosteroids. Conventional immunosuppressants were prescribed in 31 cases, while no biologic therapy was used…

…minimal T-bet expression. In addition, one patient had received anti-CD19 CAR-T therapy, and upon B cell repopulation, only naïve dsDNA-reactive B cell…

…Objectives Persistent intrarenal inflammation despite immunosuppression drives kidney damage in lupus nephritis (LN). Current guideline…

…r PBO) were enrolled in the 3-year LTE ( figure 1). Patients on PBO were rerandomized 1:1:1 to deucravacitinib (blinded); those on …

…seline data from the USEFUL study of 133 participants receiving glucocorticoid therapy for lupus arthritis (PMID: 33792659). Penalised multiple quanti…

…unosorbent assay (at the time of the kidney biopsy and prior to immunosuppressant therapy), and twelve months after treatment initiation, at the time of …

…s nephritis (LN) relapse, and whether this is influenced by the LN induction treatment.Methods Patients with biopsy-verified LN, PRS and/or MRS data, …

…erology)=0, off prednisone and immunosuppressive drugs (IS) but antimalarials were allowed. Possible predictors included were sex, age at dia…

…al sepsis and ventilator-associated pneumonia but improved with intensive care management.This case highlights the diagnostic challenge of gallstone ileu…

… capacity (FVC) less than the lower limit of normal (LNN) after bronchodilation. We examined fractional exhaled nitric oxide (FeNO), blood biom…