…harbored enhanced amino acid metabolic activity. Interestingly, neoadjuvant chemotherapy could block this status and restore the antitumor immune balanc…
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7,227 articles · page 232 of 603…s median survival. The standard of care, consisting of surgery, chemotherapy, and radiation has not changed in over 20 years, and no phase I…
…lls in the tumor is the major key for successful immunotherapy. Checkpoint blockade, therapeutic vaccine, bi-specific T cell engager (TCE) and CAR-…
…Background Renal cell carcinoma (RCC) responds to immunotherapy despite its low tumor mutational burden (TMB). Interestingly, t…
…jor histocompatibility complexes (MHCs) are critical targets in immunotherapy and cancer treatment. However, traditional E. coli expression s…
…therapeutic modality using bispecific antibodies we refer to as Amplify•R. These antibodies engage endogenous cytokines in vivo and enhan…
…alf of advanced bladder cancer patients benefit from checkpoint immunotherapy and antitumor responses are often transient.Interleukin-12 (IL-…
…o studies in mouse models of ovarian cancer in combination with oncolytic virotherapy.…
…pandemic era are strongly associated with receipt of SARS-CoV-2 mRNA vaccines, but it appears that non-mRNA vaccines may not have similar eff…
…es after intravesical delivery. Furthermore, when combined with PD-1 blockade, engineered EcN amplified the antitumor antibody response and p…
…Tm-A2DM (10-100µg), and tumors harvested at 48 hr. For low-dose RPT, mice were administered 225Ac-A2DM or 177Lu-A2DM, and tumors co…
…a retrospective chart review of patients treated with bsAbs for standard of care therapy at a Brown University Health site from 2018 to 2025. Baseline c…