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… tumor cells and host immune system and monitoring responses to immunotherapy. Here we report on the generation of dual reporter syngeneic ce…

… higher MPO activity in circulating neutrophils correlated with chemotherapy resistance.Conclusions Overall, our study demonstrates the crit…

…Background Renal cell carcinoma (RCC) responds to immunotherapy despite its low tumor mutational burden (TMB). Interestingly, t…

…Background Immunotherapy has emerged as an attractive approach to improve outcomes for p…

…jor histocompatibility complexes (MHCs) are critical targets in immunotherapy and cancer treatment. However, traditional E. coli expression s…

…onstrating potential of enLIGHTEN™ to guide indication-specific immunotherapy development.…

… While significant progress has been made in the development of immunotherapy for ccRCC, there are still many unanswered questions about the …

…res the need for improved strategies. GBM remains refractory to immunotherapy, potentially due to its immunosuppressive tumor microenvironmen…

…nd limiting the effectiveness of antitumor therapies, including immunotherapy. Tumors alter the expansion and functions of myeloid cells by a…

…ed molecular drivers. Given the scarcity of biomarkers to guide immunotherapy in TETs, we conducted an integrative analysis to characterise i…

…lone require multimodal therapy. For decades, this has included radiation therapy and/or chemotherapy. This approach can be curative for many pat…

…otherapy with methylprednisolone and plasmapheresis, as well as palliative radiotherapy, she experienced rapid functional deterioration.Case 2: Serum I…