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Helicobacter pylori infection, treatment and colorectal cancer risk by genetic predisposition: evidence from two randomised trials

gutjnl · abstract · 2026-06-30 · 4 matching annotations

90.8%

MITS SIT Shandong Intervention Trial CRC colorectal cancer

… with successful eradication (HR=0.38, 95% CI 0.15 to 0.94). In MITS, no overall benefit was observed 13.8 years after treatment (HR…

IDDF2026-ABS-0386 Genetically determined heterogeneous treatment effects of helicobacter pylori eradication for targeted gastric cancer prevention: a post-hoc analysis of two randomized controlled trials

gutjnl · abstract · 2026-06-26 · 3 matching annotations

92.2%

MITS SIT Shandong Intervention Trial NCT00155389 gastric cancer ChiCTR-TRC-10000979 GC H.pylori

…pylori treatment, with their CATEs aggregated into the PTBS. In MITS, targeting the high-treatment-benefit subgroup reduced GC risk …

IDDF2026-ABS-0384 Genetically influenced metabotypes characterize gastric cancer susceptibility and enable precision prevention

gutjnl · abstract · 2026-06-26 · 1 matching annotations

85.6%

UK Biobank MITS UKBB UGCED SIT Upper Gastrointestinal Cancer Early Detection program gastric cancer

…bolomic data from 436,480 participants across five cohorts: the UK Biobank (UKBB) Discovery (n=145,857) and Test (n=284,694) cohorts, and …

IDDF2026-ABS-0523 Genetic susceptibility to helicobacter pylori infection and its genetic association with gastric cancer

gutjnl · abstract · 2026-06-26 · 1 matching annotations

82.1%

MITS UK Biobank UKB UGCED Upper Gastrointestinal Cancer Early Detection Program SIT gastric cancer GC

…raging the Mass Intervention Trial in Linqu, Shandong Province (MITS; n=2804), with replication in the Upper Gastrointestinal Cancer…