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ACUMEN

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Articles mentioning ACUMEN

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Acute High Dose Melatonin for Encephalopathy of the Newborn (ACUMEN) Study: a protocol for a multicentre phase 1 safety trial of melatonin to augment therapeutic hypothermia for moderate/severe hypoxic ischaemic encephalopathy

bmjopen · abstract · 2025-08-22 · 1 matching annotations

83.0%

ACUMEN melatonin hypoxic-ischaemic encephalopathy (HIE)Medicines and Healthcare products Regulatory Agency

…te the risk of DLE per dose level, with a target level of <33%. ACUMEN will establish a network of centres with standardised neurocrit…