…-2R targeting to be significantly augmented by combination with Entinostat. These effects are associated with TCRVβ13/IL-2R targeting augm…
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10,506 articles · page 174 of 876…nine head and neck cancer (HNC).Results In mouse models of HNC, BSCgal enhances both radiodynamic and immune responses of SABR. It inc…
…ssociated with differential response to targeted inhibitors and ICi. The mesenchymal-like cell state elicits an invasive phenotype …
…nical outcomes but superior immunotherapeutic responsiveness to pembrolizumab in GC. Transcriptomic and phenotypic analyses revealed that tum…
…neic MC38 tumor model where a 4-1BB Multabody was compared with urelumab. For safety assessment, we performed histopathologic analysis o…
… responses to intravesical CS/IL-12.Conclusions Intravesical CS/caIL-12 treatments have been generally well-tolerated. Five dose levels…
…fects of gold salt on surface immune marker. Aurothiomalate and Chloroaurate upregulate ICOSL, PDL-1 and MHC-1 expression on pancreatic canc…
…esponses including autophagy (figure 2C). Finally, single agent encorafenib was administered in the 3rd and 4th line in two patients with l…
…e safety profile with no systemic T-cell activation.Conclusions RNDO-564 elicits robust Nectin-4-dependent in vitro and in vivo anti-tum…
…dvantages over reference CEA antibodies such as tusamitamab and labetuzumab.Results Our novel CEA mAb, P601 binds with high affinity and se…
…y, we provide supporting preclinical data supporting the use of BDC-4182 in combination with CPI in gastric cancer patients.Conclusions …
…rm and shows significantly reduced cytokine release.Conclusions CX-908 shows strong anti-tumor efficacy and an improved tolerability p…