…ve biomarker in patients with aUC commencing EV with or without pembrolizumab.Methods We conducted a multicenter, retrospective real-world an…
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10,506 articles · page 447 of 876…suggest that specific medication classes, particularly baseline opioids and beta-blockers, may strongly contribute to this association.…
… humanized mice models treated with immunotherapy combinations (nivolumab, ipilimumab, cobolimab)-coupled LSD1 inhibitor significantly re…
…LITT+PEM) or non-LITT surgery (biopsy or resection) followed by pembrolizumab (NLS+PEM). After 21 patients, randomization was halted when eme…
…gnaling in sustaining tumor growth in this model. Additionally, C3aR-AT treatment led to a ~23.9-fold increase in neutrophil infiltrati…
…mmunother Cancer. 2020;8:A371.Sun L, Fayette J, Salas S, et al. Tisotumab vedotin in head and neck squamous cell carcinoma: updated analysis from…
…ty. In Cohorts A-C of the ongoing Phase I study ( NCT04684563), huCART19-IL18 exhibited a manageable safety profile and encouraging antitumor…
…igen-specific T cell (TAA-T) products targeting WT1, PRAME, and survivin have been safely administered to patients with r/r disease with…
…carcinoma (HNSCC)—which shares histology but responds poorly to PD-1 inhibitors—may offer new insights into CSCC pathogenesis and immune respon…
…Background SECN-15 is a high-affinity antisense oligonucleotide (ASO) designed to …
…). (D) Schematic: ROSA26 x Ai9 mice treated with tdRT→αPD-1 and tamoxifen, followed by SLN mapping and CITE-seq of sorted tdTomato+ cells…
…s of cytotoxic function. Notably, even in resting CD8+ T cells, ME1 OE induced higher expression of Fasl, Gzmk, and Gzmb. According…