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…rent treatments are limited to two nitroheterocyclic compounds: nifurtimox and benznidazole (BZN). Each has significant limitations, inclu…

…les of serendipity in drug discovery, the antipyretic action of phenacetin was accidentally discovered because of its use by clinicians wh…

…ntigraphy was also used (41 patients, 45%). Management involved methotrexate discontinuation in 79% of the cases. Fracture healing and pain …

…mpared with CRP (area under the curve=0.836).Conclusions C3 and calprotectin are elevated in early PsA and are responsive to treatment. Thes…

…Interventions Newborns were randomised 1:1 to receive 0.1 mL of BCG Danish intradermally plus OPV, either within 48 hours of admission to …

…els, the autophagy inhibitor chloroquine significantly enhanced anlotinib+anti-PD-1 efficacy—likely by inducing more apoptosis of CAFs an…

…tory effects of curcumin, we aimed to investigate the effect of curcumin supplementation on fatigue and musculoskeletal health (primary …

…sy patients do not respond to current antiepileptic treatments. Lacosamide (LCM), a third-generation ASM, has demonstrated established eff…

… we aim to examine whether there is a statistical difference in CPAP compliance within our 2019 (pre-COVID) and 2022 (post-COVID) co…

… were approved in Japan, and the approvals occurred later. Most therapeutics approved in Japan had previously received EUA in the USA, with …

…al anesthesia (TIVA with propofol), including opioid analgesia (fentanyl). Intraoperatively analgesia is estimated by hemodynamics (obje…

…sound-guided and primed with ropivacaine. Two patients received ropivacaine infusions; five received lidocaine programmed intermittent bolu…