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…nt mice. In vitro stimulation of primary mouse fibroblasts with spermidine induced Stat3 phosphorylation and subsequent Apoe upregulation.…

…fied bowel wall thickness (BWT) (OR=2.047, 95%CI: 1.345-3.114), fecal calprotectin (FC) (OR=1.012, 95%CI: 1.006-1.019), white blood cell count (WB…

…udy tested the hypothesis that age-associated immunoglobulin G (IgG) accumulation exacerbates susceptibility to hepatic steatosis a…

…co-cultures, neurons expressing mutant NFASC failed to suppress LPS-induced pro-inflammatory cytokine production and M1 macrophage polariza…

…ith T2DM and cirrhosis is challenging due to limited options of anti-diabetic agents and the risk of hypoglycaemia. We aimed to determine the associ…

… with stage II or III disease, derived substantial benefit from adjuvant chemotherapy compared with surgery alone (SYSU-CRC, P = 3.68 × 10-5; SYSU-SA…

…S. anginosus infection was established by alternating gavage of N-methyl-N-nitrosourea (MNU) and the respective bacterial suspensions. Gastric tissues…

…pressive niche that facilitated tumor progression. Importantly, pharmacological inhibition of IGF1R significantly reversed the immunosuppressive microenvironment a…

…egulator of intestinal homeostasis, and studies have shown that indole-3-acetic acid (IAA) can activate AhR, thereby exerting a protective effect in intes…

…daily for 12 weeks, alongside their standardized treatment with mesalazine. Stool assessment for 16S rRNA sequencing, faecal calprotectin …

…i-omics analyses of public and in-house HCC datasets identified Neurotensin (NTS) as enriched in peri-necrotic regions. Metabolic stress models w…

…regulate these genes (IDDF2026-ABS-0246 Figure 2). Furthermore, fostamatinib exhibited the strongest binding affinity with FAAH, with a bind…