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…autoantibodies (OR [95% CI] = 0.17 [0.03-0.86], p-value 0.032). Ficolin-3 associated positively with 10 inflammatory plasma proteins, int…

…ar necrosis of both femoral heads. Current medications included mycophenolate mofetil, methylprednisolone, nifedipine, bosentan, and aspirin, along w…

…s including haematology, ii) no increase in medication and iii) prednisolone dose <=5mg/day on at least 2 consecutive visits at least 6 mont…

…logic disorder. Cumulatively, serositis was also more frequent. SLERPI demonstrated comparable performance to the ACR/EULAR criteria: …

…and 4%-13%, respectively); biologic use was primarily off-label rituximab.…

…b in 25, belimumab in 16, obinutuzumab in 2, voclosporin in 21, tacrolimus in 6, cyclosporin-A in 4 and azathioprine in 3 patients. Six pa…

…Objectives Belimumab (BEL) is a B-cell modulating anti-BLyS mAb approved for SLE (20…

…CR 2019, SLICC and/or ACR 1997 diagnostic criteria treated with Belimumab in monotherapy. Data were collected from medical records of SLE…

…prine (16%), methotrexate (9%), and mycophenolate mofetil (9%). Rituximab was used in 7% of severe or treatment-resistant patients.Conclu…

…s exhibit mitochondrial expansion and a hypermetabolic profile. IFN-alpha selectively augments basal respiratory and glycolytic flux, imp…

…ectives Effective, well-tolerated therapies are needed for SLE. Deucravacitinib is an oral, selective tyrosine kinase 2 (TYK2) inhibitor under …

…02 Figure 1Conclusions Gene-expression signatures, particularly interferon and plasmablast modules, outperform legacy diagnoses in predict…