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…therapy), and 18 months of adjuvant therapy with relugolix plus enzalutamide. Primary outcomes include pathologic CR rate and minimal residu…

…, coupled with rapid clinical and biochemical improvement after atorvastatin discontinuation, supported a diagnosis of rhabdomyolysis due to…

…tinum salts (carboplatin, oxaliplatin, cisplatin), and taxanes (paclitaxel, docetaxel).Methods This single-centre, retrospective study was…

…optic neuropathy (LHON) carrying the m.11778G>A MT-ND4 variant. Idebenone, a synthetic coenzyme Q10 analogue, is the only approved treatm…

…sition, and lifestyle factors to determine whether sex-specific insulin strategies provide meaningful clinical benefit.PROSPERO registr…

…rgency Department (ED) attendance and it is often undertreated. Entonox (nitrous oxide) is effective but carries approximately 98.9 kg …

…Objective To determine whether extending caffeine therapy through 43 weeks’ postmenstrual age (PMA) decreases int…

…ed antitumor immunity in combination-treated tumors.Conclusions Telmisartan depletes tumor PD-L1 but has significant PD-L1-independent clin…

…olerability, pharmacokinetics (PK) and pharmacodynamics (PD) of bepranemab.Methods UP0047 ( NCT03464227) and UP0065 (NCT03605082) were pha…

…nesthetics and adjuvant.Method Commonly used local anesthetics (lidocaine, mepivacaine and ropivacaine) and adjuvants (dexamethasone, dex…

…as agonists at serotonin 5-HT2A receptors in the brain, include psilocybin, 5-methoxydimethyltryptamine, and N,N-dimethyltryptamine (trypt…

…of aripiprazole/sertraline medication combination compared with quetiapine for bipolar depression. The study is conducted in the UK Nation…