ButylmalonateSuccinatemyocardial ischemia
… adult cardiomyocytes were used as in vitro and in vivo models. Butylmalonate prodrugs were synthesized and tested. Isolated mitochondria wer…
3articles mentioning drugs
18drug mentions
1distinct drugs extracted
0%of mentions human-reviewed
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succinate
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Articles mentioning succinate
3 articles · page 1 of 1Succinatemulti-organ failuresepsisSepsis-inducedsystemic inflammation
…erved tight junction integrity and barrier function.Conclusions Succinate promotes epithelial pyroptosis via SUCNR1-dependent upregulatio…
IL-10fumarateIL-1βSuccinateleft ventricular failureright ventricular failurePatientsright ventricular failureLV failureRV failure
… of fumarate (R2=0.65, p=0.008). The anti-inflammatory cytokine IL-10 was lower in LV failure (0.3 ± 0.13 pg/ml) than controls (0.51 …