MaralixibatNAPPED ConsortiumEUProgressive Familial Intrahepatic Cholestasis (PFIC)MDR3FIC1
…Maralixibat, an inhibitor of the ileal bile acid transporter, is approved i…
8articles mentioning drugs
16drug mentions
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maralixibat
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Articles mentioning maralixibat
8 articles · page 1 of 1maralixibatBezafibratenaltrexoneursodeoxycholic acidcholestyraminecholestatic liver diseaseischaemic cholangiopathytacrolimus-based immunosuppression
…tting. Ileal bile acid transporter (IBAT) inhibitors, including maralixibat, are promising therapies for genetic cholestatic conditions. We…
maralixibatMRXIBATiICONICALGSMERGEAlagille Syndrome (ALGS)
…ged. Reductions in TB and DB were observed after treatment with maralixibat. No clinically meaningful changes in ALT or AST were observed w…
ursodeoxycholic acidobeticholic acidMaralixibatfibroblast growth factor 19 (FGF19) analoguesFGF19 analoguesapical sodium-dependent bile acid transporter (ASBT) inhibitorsPBCintrahepatic cholestasisMDR3 deficiencyprimary biliary cholangitis (PBC)+3 more
…lusions Mdr2-/- mice show a limited response to BAAs (including ursodeoxycholic acid), consistent with humans who have severe loss-of-function ABCB4…
MaralixibatMRXMRX-MRXProgressive Familial Intrahepatic Cholestasis (PFIC)EUPFIC
…lting in disrupted bile composition, cholestasis, and pruritus. Maralixibat, an inhibitor of the ileal bile acid transporter, is approved i…
MaralixibatMRXProgressive Familial lntrahepatic Cholestasis (PFIC)ICONICAlagille syndrome (ALGS)ALGS
… with markedly reduced health related quality of life (HRQoL). Maralixibat (MRX), an oral minimally absorbed ileal bile acid transporter (…
loperamideMaralixibatileal bile acid transporter (IBAT) inhibitorsByler diseaseArch Pathol Lab Medliver transplantationSurgical biliary diversion
…edure.The frequency of bowel movements decreased as well as the loperamide dose. Liver histology showed a reduction in hepatic steatosis f…