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…s introduced, initially referring to TB resistant to isoniazid, rifampicin, and at least three of the six main classes of second line drug…

…t (2%), and paediatric (2%).Conclusion and Relevance Nearly all linezolid prescriptions met at least one criterion for TDM, with around 6…

…cially in prolonged or high-risk treatments. Determining plasma linezolid concentrations in selected patients could enhance treatment saf…

…er a third of survivors, better treatments are urgently needed. Linezolid, a well-established treatment for pneumonia and complicated ski…

…ntial for antibiotics with a narrow therapeutic window, such as linezolid, where subtherapeutic exposure may compromise efficacy and over…

…6% maintenance of the original regimen.Conclusion and Relevance Linezolid plasma monitoring is essential in hospitalised patients, especi…

…ntibiotic, but it can cause side effects, such as liver damage. Linezolid is another valid alternative.Pharmacokinetic monitoring of line…

…o mitigate adverse effects and ensure therapeutic success.While linezolid does not affect human cytoplasmic ribosomes, it can impair mito…

…Linezolid is an antibiotic of the oxazolidinone class which is highly eff…

…armacopoeia.Results Seven out of 13 formulations were selected: Amoxicillin 250 mg/5 mL, Amoxicillin–clavulanic acid 100 mg/mL–12.5 mg/mL, …

…discharge, or death). Antimicrobials considered for ST included levofloxacin, metronidazole, linezolid, clindamycin, fluconazole, ciprofloxa…

… were reviewed, mainly meropenem (39.7%), ertapenem (21.2%) and linezolid (6.2%). Most treatments were empirical (52.4%) or targeted (42.…