…ow (see section on Current treatments). The antifibrotic drugs, pirfenidone and nintedanib, are established treatments for idiopathic pulmo…
Tocilizumab
This drug is selected. Its supporting articles are shown below.
Articles mentioning Tocilizumab
53 articles · page 1 of 5…atients were enrolled based on published data supporting use of rituximab or tocilizumab. Each arm aimed to enroll 15 patients. Primary e…
…for systemic sclerosis (SSc) treatment, which newly recommended mycophenolate mofetil (MMF), rituximab (RTX), and tocilizumab (TCZ) as options for sk…
…ute ischaemic stroke (AIS). Preclinical research indicates that tocilizumab, an interleukin-6 receptor antagonist, can attenuate ischaemia-…
…tional studies targeting IL-6 in this population remain scarce. Tocilizumab is a humanised monoclonal antibody that inhibits IL-6 signallin…
…was uncommon in both groups (10% in trials vs 1% in real life). Tocilizumab was administered in all trial cases (20/20) versus 66% (200/303…
…mmol/L) and acute flaccid paralysis after his third intravenous tocilizumab infusion. He had no prior neurological or electrolyte disturban…
…1.38), TNFi 1.01 (0.66 to 1.54), rituximab 1.14 (0.71 to 1.84), tocilizumab 1.48 (0.92 to 2.40). LDA and remission rates were unaffected by…
…trexate use increased until 2020 and plateaued thereafter while tocilizumab prescriptions rose, reaching over 25% in 2022. Male sex and bas…
…or inhibitors (TNF-i) use (OR 0.502, 95% CI 0.312 to 0.808) and tocilizumab use (OR 0.493, 95% CI 0.304 to 0.799) were associated with sarc…
…citinib or upadacitinib), rituximab, tocilizumab, methotrexate, mycophenolate mofetil, or glucocorticoids (>=10 mg prednisone equivalent daily) for m…
…n TCZ monotherapy, the most common combination therapy was with methotrexate(35%). In SSc-ILD patients, a significant decline of %pFVC from …