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Sacituzumab

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Sacituzumab2

Articles mentioning Sacituzumab

2 articles · page 1 of 1

1166 Avidity engineered multifunctional antibodies that strongly activate and expand anti-tumor immunity in situ, turning cold patient tumor tissue hot and exerting durable tumor control in mice

jitc · abstract · 2025-11-04 · 1 matching annotations

90.9%

trastuzumab Her2 sacituzumab cetuximab TROP2 EGFR cancer NRG mice

…ROP2, or EGFR Boosters demonstrated superior tumor control than trastuzumab, sacituzumab, or cetuximab analogue treated mice respectively. …

Preclinical evaluation of antitumor activity and toxicity of TROP2-specific CAR-T cells for treatment of triple-negative breast cancer

jitc · abstract · 2025-09-03 · 1 matching annotations

89.4%

Sacituzumab Triple-negative breast cancer TNBC NSG mice Chimeric antigen receptor T cell (CAR-T) therapy breast cancer

…onstructed based on the clinically-validated humanized antibody Sacituzumab and expressed in primary human T cells using a retroviral vecto…