Browse drugs

…ospective cohort (45 patients, 127 visits), with comparisons to BILAG, SLEDAI, and LFA-REAL. The PRO component comprises four VAS ite…

…, urinary casts, and pyuria versus patients without visits with SLEDAI >8. Low complement and high DNA binding were common irrespectiv…

…reflection of lupus activity than conventional C3 and C4 levels.sTCC were particularly informative for both active SLE and nephritis…

…ti-dsDNA, C3, C4, SLEDAI, proteinuria, and glucocorticoid dose. ApoB100 IC IgM was associated with renal and hematologic involvement, d…

…vity (LLDAS), surpassing classic biomarkers like anti-dsDNA and SLEDAI. Mixed-effects logistic regression yielded data-driven cut-offs…

…s/minus 1.8) and correlated with HAQ-DI (r=0.72). Patients with SLEDAI greater than 6 reported greater exertion (16.2 plus/minus 1.9 v…

…irmation by a rheumatologist or nephrologist, or an increase in SLEDAI by 3 or more. Patient demographics, clinical phenotypes, and me…

…nalysis included the aggregated placebo arms from phase 2 and 3 anifrolumab trials (MUSE, TULIP-1, TULIP-2) in moderate-to-severe SLE. Phys…