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SEL

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SEL4

Articles mentioning SEL

4 articles · page 1 of 1

P62 Seladelpar linked to sustained reduction in cholestatic markers with consistent safety profile in PBC up to 48 months in ASSURE

gutjnl · abstract · 2026-06-23 · 11 matching annotations

87.5%

seladelpar SEL ursodeoxycholic acid (UDCA) who have an inadequate response to UDCA primary biliary cholangitis (PBC)PBC NCT04620733 NCT03301506

…n (B), ALP % change from BL (C) through 36 months of open-label seladelpar treatmentn/N = number of responders at each time point/total nu…

P54 36 months of treatment with seladelpar is associated with stable or improved liver stiffness in patients with primary biliary cholangitis

gutjnl · abstract · 2026-06-23 · 5 matching annotations

84.0%

seladelpar ursodeoxycholic acid (UDCA) who have an inadequate response to UDCA SEL UDCA primary biliary cholangitis (PBC)PBC NCT03301506 NCT04620733

…fness by baseline subgroups.Baseline was defined at the time of seladelpar initiation.n = the number of evaluable patients at each time po…

P57 Improvements in moderate-to-severe pruritus patients with primary biliary cholangitis treated with seladelpar in up to 30 months of ASSURE

gutjnl · abstract · 2026-06-23 · 4 matching annotations

84.8%

Seladelpar SEL Numeric Rating Scale primary biliary cholangitis NCT04620733 PBC PBC-40 NCT03301506

…ry cholangitis (PBC) and significantly impairs quality of life. Seladelpar (SEL), a first-in-class delpar (selective PPAR-delta agonist), …

4CPS-074 Assessment of elafibranor for the treatment of primary biliary cholangitis

ejhpharm · abstract · 2026-03-18 · 1 matching annotations

81.2%

ELAFIBRANOR SELADELPAR OBETICHOLIC ACID ELF ursodeoxycholic acid SEL OCA UDCA primary biliary cholangitis PBC

…% CI 23.7 – 50.3)) SELADELPAR (ARR = 40.9 (95% CI 28.1 – 53.8)) ELAFIBRANOR (ARR = 47.2 (95% CI 36.4 – 57.9)) ARR = 10.2 (-6.9 ; 27,3) p = …