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SD208

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Articles mentioning SD208

3 articles · page 1 of 1

BS39 Myofibroblast-derived small extracellular vesicles are regulators of electrophysiology and mediators of hypertrophy in human cardiomyocytes

heartjnl · abstract · 2025-08-13 · 3 matching annotations

88.0%

SD208 TGF-β1 Hypertrophic cardiomyopathy HCM heart failure surgical myectomy

…ed and downregulated in (A) HCM myofibroblasts with and without SD208 treatment. (B) hiPSC-CM with and without sEV treatment. Several…

P.035 Primary cilia shortening of systemic sclerosis dermal fibroblasts can be modulated by aurora a kinase activity to reduce fibrotic phenotype

jsrd · abstract · 2026-06-05 · 2 matching annotations

94.1%

Tubacin SD208 KD025 MLN8054 AURKA TGF-β ROCK2 Systemic sclerosis (SSc)SSc

…d inhibitors of TGFβR1 (SD208, 1 μM), ROCK2 (KD025, 5 μM),HDAC (Tubacin, 10 μM),and Aurora A kinase (AURKA) (MLN8054, 10 μM). CAV1 knoc…

D Myofibroblast-derived small extracellular vesicles are regulators of electrophysiology and mediators of hypertrophy in human cardiomyocytes

heartjnl · abstract · 2025-08-13 · 1 matching annotations

91.4%

SD208 TGF-β1 DiI Hypertrophic cardiomyopathy Cardiff University La Trobe University myocardial fibrosis cardiovascular diseases University of Melbourne heart failure+2 more

…ed by qRT-PCR and immunofluorescence. TGF-β1 receptor inhibitor SD208 (3 μM) treatment exerted antifibrotic effects, reducing the exp…