6articles mentioning drugs
7drug mentions
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PRAME
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Articles mentioning PRAME
6 articles · page 1 of 175.2%
B7-H3PRAMEgraft-versus-host diseasediffuse midline gliomaDMG
…ells, both with and without B7-H3 CAR modifications.Results Our B7-H3 CAR, PRAME-specific T cells showed a mean transduction efficien…
survivinWT1PRAMEr/r solid tumorsosteosarcomaWilms tumorChildren’s National Hospital’s Institutional Review BoardneuroblastomaDepartment of Defense Peer Reviewed Cancer Research Program Career Development Award
…igen-specific T cell (TAA-T) products targeting WT1, PRAME, and survivin have been safely administered to patients with r/r disease with…
IMA203PRAMEPRAME-derivedPRAME-directedadvanced melanomaImmatics US, Inc.
…ing success and improve final product characteristics. Notably, IMA203 manufacturing achieved a 95% success rate at the RP2D (1-10x10 …
IMA203cyclophosphamidemRNA-4203PRAMEfludarabinesynovial sarcomaImmatics US, Inc.SSadvanced cutaneous melanoma
…ed by ORR, DOR, DCR, and PFS. Additionally, pharmacokinetics of IMA203 transgene levels in peripheral blood will be evaluated. The tri…
IMA203nivolumabpembrolizumabipilimumablifileucelrelatlimabPRAMEmetastatic melanomacutaneous melanoma
…2 and Flu 30 mg/m2 x 4 days, followed by a one-time infusion of IMA203 (1-10x 109 TCR T cells), and low-dose IL-2 (1 M IU QD x5 days, …