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PD-1-targeted CRISPR-Cas9

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PD-1-targeted CRISPR-Cas91

Articles mentioning PD-1-targeted CRISPR-Cas9

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601 Assessment of CRISPR PD-1 edited tumor-infiltrating lymphocytes in infusion products for adoptive cell therapy in metastatic melanoma

jitc · abstract · 2025-11-04 · 1 matching annotations

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CRISPR-Cas9 PD-1 targeting immune checkpoint inhibitors PD-1-targeted CRISPR-Cas9 metastatic melanoma Adoptive T cell therapy The Danish National Committee on Health Research Ethics

…we present initial data from the first-in-human trial employing CRISPR-Cas9 to knockout PD-1 in TILs from patients with metastatic melanoma…