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Active filtersEntity: O-GlcNAcylated CLDN18.2 ×

O-GlcNAcylated CLDN18.2

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O-GlcNAcylated CLDN18.21

Articles mentioning O-GlcNAcylated CLDN18.2

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KRAS mutation-driven O-GlcNAcylation of CLDN18.2 enhances the progression of pancreatic cancer and reduces the efficacy of CLDN18.2-targeted therapy

gutjnl · abstract · 2026-05-12 · 4 matching annotations

81.0%

MRTX1133 CLDN18.2 O-GlcNAcylated CLDN18.2 KPC mice pancreatic ductal adenocarcinoma gastric and gastro-oesophageal junction cancers PDAC

…on and suppresses tumour progression. Therapeutically, low-dose MRTX1133 (KRASG12D inhibitor) reduces O-GlcNAcylation and synergises wit…