Browse drugs

…nically approved anti-CTLA-4 antibodies, such as ipilimumab and tremelimumab, target Tregs to exert anti-tumor effects. However, their use r…

… humanized mice models treated with immunotherapy combinations (nivolumab, ipilimumab, cobolimab)-coupled LSD1 inhibitor significantly re…

…tiplex imaging. bioRxiv. 2022.Ascierto PA, et al. Sequencing of ipilimumab plus nivolumab and encorafeni bPlus binimetinib for untreated B…

…s (n=7, 47%), nivolumab/ipilimumab (n=3, 20%), atezolizumab and durvalumab (n=2 each, 13%), and cemiplimab and toripalimab (n=1 each, 7%) …

…2 and Flu 30 mg/m2 x 4 days, followed by a one-time infusion of IMA203 (1-10x 109 TCR T cells), and low-dose IL-2 (1 M IU QD x5 days, …

… be enrolled in the first stage. If ≥2 patients respond to NIVO+RELA, the study will continue enrollment for a total of 20 patients.…

… tumors and tumor draining lymph nodes to unveil the effects of APMV-4 ISV on host immune responses. Ex vivo splenocyte stimulation wa…

… reduction in NK and B cells. When 177Lu-PSMA was combined with pembrolizumab, we saw dynamic changes in non-Treg T cell subsets (CD4+ and CD…

…lick AC, Jiang J, Avila A, … Margolin K. Combined nivolumab and ipilimumab in melanoma metastatic to the brain. The New England Journal of…

…lliam NW Jr, Weissferdt A, et al. Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung canc…

…40425-018-0382-2Hellmann MD, Paz-Ares L, Bernabe Caro R, et al. Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer. N Engl …

…K Assay; and 21 patients with advanced ccRCC being treated with ipilimumab and nivolumab (ipi+nivo), assessed pre-treatment and prior to c…