cyclophosphamideIL-2IL-21IL-15melanomapancreatic ductal adenocarcinomametastatic PDACFOLFIRINOX
…the presence of IL-2/IL-15/IL-21. Each infusion was preceded by cyclophosphamide lymphodepletion and followed by IL-2 support. Clinical response…
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Cyclophosphamide
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Articles mentioning Cyclophosphamide
133 articles · page 9 of 121338 Multi-cohort phase II study of autologous centrally manufactured tumor infiltrating lymphocytes
cyclophosphamidefludarabineIL-2melanomaovarian canceranaplastic thyroid cancerMD Anderson IRB
…neration. After successful TIL production, lymphodepletion with cyclophosphamide (60mg/kg/day IV on days -7 and -6) and fludarabine (25mg/m2 IV …
cyclophosphamidemelanomaneuroblastomaNBcolorectalAdoptive cell therapiesC57BL/6 mice
…ntation into C57BL/6 mice. These cell lines were engineered for cyclophosphamide (Cy) resistance to model relapsed/refractory NB and support lym…
cyclophosphamideRhabdomyosarcomasolid tumorsRMSChimeric antigen receptor (CAR) T therapyCART therapy
…ntramuscularly into C57BL6 mice. Following preconditioning with cyclophosphamide, murine CART cells specific for the sarcoma antigen B7-H35 are …
177Lu-PSMA-617cyclophosphamideCymetastatic castration-resistant prostate cancermetastatic castration-resistant prostate cancer (mCRPC)mCRPCRPTNCT03873805
…responses, and extended durability. By using the two therapies (177Lu-PSMA-617 and PSCA-CAR T cells) that are FDA approved or in clinical deve…
Cy/FlucyclophosphamidefludarabineIL-12 GEMysOsteosarcomarhabdomyosarcomaNational Institutes of HealthIL-12 GEMy therapy
…ated by an immunosuppressive myeloid infiltrate. Treatment with Cy/Flu depleted most circulating immune cells and TAMs. Cy/Flu plus IL…
cyclophosphamideIL-2Ovarian cancer
…tumors. Six to eight weeks later, mice were lymphodepleted with cyclophosphamide and received TCRMsln-engineered T cells and Msln peptide-pulsed…
fludarabinecyclophosphamiderecombinant human IL-2cancerosteosarcomaUniversity of Wisconsin Institutional Animal Care and Use Committeehuman malignancies
…ex vivo expanded allogeneic NK cells after lymphodepletion with fludarabine and cyclophosphamide. Canines were given subcutaneous recombina…
nivolumabcyclophosphamidepembrolizumabfludarabinealdesleukinhematologic cancersWCG IRBmetastatic HPV-associated cancersmetastatic HPV-associated epithelial cancersepithelial cancers
…nt with anal cancer previously treated with 5 agents, including nivolumab. The duration of the complete responses is 8 months and 9 month…
ANV419fludarabinecyclophosphamidemelanomaPragmaTIL network
… The BaseTIL-03M trial demonstrates that combining TIL-ACT with ANV419 is feasible and well tolerated, with no dose-limiting toxicitie…
PembrolizumabAnthracyclineCyclophosphamidePaclitaxelCarboplatinbreast cancerchemotherapyTNBC
… of definitive surgery who had received chemotherapy along with Pembrolizumab as neoadjuvant settings. After the definitive surgery the biops…
rhIL-15cyclophosphamideNational Cancer Institutesolid tumorsrelapsed/refractory solid tumorsNK cell immunotherapiesNCI
…lophosphamide without (Cohort A) and with (Cohort B) continuous rhIL-15 infusion. Correlative studies included spectral flow cytometry,…