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…latory agents interleukin-2 (IL-2) and the microbial metabolite butyrate are under investigation for tumor microenvironment modulation. …

…s the responsiveness of CD8+ T-cells with exhausted phenotypes. Butyrate demonstrated an ability to alter the expression of immune check…

… patients. High-risk patients exhibited enhanced sensitivity to dasatinib, docetaxel, erlotinib, and gefitinib ( figure 1).Conclusions Th…

…n vivo and in vitro through the gut-lung axis. Mechanistically, butyrate activated GPR109A-FOXO1 signaling and suppressed fatty acid oxi…

…arger-scale study will be warranted to evaluate the efficacy of tributyrin supplementation in alleviating depressive symptoms. This pilot …

…application in human CRC and the underlying mechanisms by which butyrate interacts with specific CD8+ T cell subsets to regulate immunit…

…sfunction, microbiome alterations and subclinical inflammation. Butyrate and HDAC inhibitors reversed these effects, indicating that DUO…