MICA/MICBB7-H3Pancreatic ductal adenocarcinoma (PDAC)PDAC
…sion of B7-H3 (90% ± 1.4% vs. 72% ± 6.6%, P = 0.005) and MFI of MICA/MICB (5479 ± 1680 vs. 1069 ± 691, P = 0.003), compared to non-radiat…
7articles mentioning drugs
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B7-H3
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Articles mentioning B7-H3
7 articles · page 1 of 1B7-H3anti-B7-H3 antibody‒drug conjugatecolorectal cancer
…and profibrotic pericytes specifically expressed high levels of B7-H3, the former being an independent factor for poor prognosis in p…
B7-H3B7-H3-targeted ADCsimmunotherapyclinicaltrials.govbrain metastasesmetastatic triple-negative breast cancer (TNBC)metastatic TNBCTNBC
…which yielded eight phase I/II trials examining the efficacy of B7-H3 ADCs, 12.5% (n=1/8) of which exclude patients with brain metast…
anti-PD-L1 scFvPD-L1-blocking scFvB7-H3OsteosarcomaPurdue Center for Cancer ResearchPurdue College of PharmacyPurdue UniversityOSNational Cancer InstituteV Foundation for Cancer Research
…red NK cells to express a B7-H3.CAR alongside a tumor-cleavable anti-PD-L1 scFv demonstrated significantly enhanced cytotoxicity against OS cel…
B7-H3B7-H3-targetedUniversity Hospital TübingenGerman Cancer Research CenterNUT carcinomaNGS Core Facilityimmune checkpoint blockadeOmics IT and Data Management Core Facilitystandard treatmentsDKFZ
… expression of immune checkpoint molecules and target antigens. B7-H3 emerged as particularly promising due to its uniform expression…
dexamethasoneCMD03anakinraB7-H3B7-H3-targetingChulalongkorn UniversityDiffuse intrinsic pontine glioma (DIPG)DIPGCancer Immunol Immunother
…, which resolved within 24 to 72 hours following treatment with dexamethasone and anakinra. CMD03 CAR T cells were monitored weekly in the ce…
75.9%
B7-H3PRAMEgraft-versus-host diseasediffuse midline gliomaDMG
…ells, both with and without B7-H3 CAR modifications.Results Our B7-H3 CAR, PRAME-specific T cells showed a mean transduction efficien…