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…s diagnosed in parallel to SSc diagnosis (n=3) or earlier (n=1).ACA levels remained relatively stable over a 10-year time period fr…

…ent. Distinct autoantibodies, such as anti-centromere (ACA) and anti-topoisomerase I (ATA), are associated with different clinical phenotypes, but t…

…ase I (anti-Scl-70) antibody in 28.1%, anticentromere antibody (ACA) in 24.8% and double positivity for anti-Scl-70 and ACA in 6.5%…

…24%) were positive for Scl-70, 821 (24%) for ACA, 416 (12%) for RNA POLII, and 1,331 (40%) were only ANA positive. 87% were females, mean…

… PreSSc was defined as the presence of SSc-specific antibodies (ACA, ATA, or ARA) in the absence of any other clinical manifestatio…

…ohort B included 39 patients, of whom 53.8% tested positive for ACA, 41% for anti-SCL 70 antibodies, and 5.1% for anti-RNA polymera…

…a (Hemoglobulin, Hb < 7.5 mg/dl) were treated successfully with argon plasma coagulation (APC).Conclusions GAVE is a well-established gastrointestinal c…

…E in 7/14(50%).Anti-U1RNP was most frequent(64.2%), followed by ACA(28.5%); RNApol-III was absent, and 50% lacked SSc-specific auto…

… frequently received corticosteroids (79.3% vs 67.9%, p=0.003), cyclophosphamide (43.4% vs 26%, p<0.001) and azathioprine (38.5% vs 22.3%, p=0.0…