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22drug mentions

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AB598

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Articles mentioning AB598

3 articles · page 1 of 1

170 Peripheral pharmacodynamic analysis of anti-CD39 monoclonal antibody AB598 in a first-in-human phase I trial in patients with advanced solid tumors

jitc · abstract · 2025-11-04 · 9 matching annotations

98.2%

AB598 AB598-mediated AB598-dosed zimberelimab mFOLFOX advanced solid tumors GEJ cancer NCT05891171

…tics (PK), pharmacodynamics (PD), and clinical activity of both AB598 monotherapy and AB598 in combination with zimberelimab (anti-PD…

184 Tumor biomarker analysis of anti-CD39 monoclonal antibody AB598 in a first-in-human phase I trial in patients with advanced solid tumors

jitc · abstract · 2025-11-04 · 8 matching annotations

98.1%

AB598 zimberelimab ARC-25 solid tumors advanced solid tumors

…immunological modulation, are positively correlated.Conclusions AB598 achieved complete CD39 target engagement and inhibition across …

185 Exogenous ATP drives transcriptomic changes related to DC activation that are elevated by neoadjuvant chemoradiotherapy in esophageal cancer

jitc · abstract · 2025-11-04 · 5 matching annotations

95.7%

atezolizumab docetaxel AB598 carboplatin paclitaxel NECA ESCA PD-L1 low gastroesophageal tumors TCGA

… van Laarhoven HWM. Neoadjuvant chemoradiotherapy combined with atezolizumab for resectable esophageal adenocarcinoma: a single-arm phase II…