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Active filtersEntity: AB-3028 ×

AB-3028

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Articles mentioning AB-3028

2 articles · page 1 of 1

256 Preclinical development of AB-3028, a logic-gated engineered CAR T cell product intended for the treatment of metastatic castration-resistant prostate cancer (mCRPC)

jitc · abstract · 2025-11-04 · 9 matching annotations

98.3%

AB-3028 Metastatic castration-resistant prostate cancer (mCRPC)mCRPC

…ion assay, which was dependent on SPA and TGFβR2 shRNA modules. AB-3028 exhibited anti-tumor efficacy in the PC3 indication specific xe…

303 AB-3028: Dual-targeting sequential AND logic gated CAR T cell for potential mCRPC therapeutic

jitc · abstract · 2025-11-04 · 4 matching annotations

98.3%

AB-3028 mCRPC solid tumors TCGA hematological malignancies metastatic castration-resistant prostate cancer (mCRPC)The Cancer Genome Atlas prostate tumors GTEx Chimeric Antigen Receptor T (CAR T) cell therapies

…al persistence.Methods To evaluate suitable target antigens for AB-3028, we first conducted a comprehensive in silico analyses with bul…