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…r immunotherapeutic success. Previously, we have shown that the tumor microenvironment represses mitochondrial metabolism and T cell …

…Additionally, an increased abscopal effect in the contralateral tumor was only observed in X-31 mice. Treatment of X-31 mice resulted…

… invade the dural venous sinuses or jugular veins, resulting in cerebral venous outflow obstruction. Endovascular techniques, including venous sinus stenting, angi…

…ffinity, leading to unwanted systemic effects, toxicity and low tumor biodistribution, which ultimately limits the clinical potential…

…the biological understanding of myeloid cell biology within the tumor and strategies to modulate the function and activity of myeloid…

….Conclusion Overall, the data demonstrate that RP1 remodels the tumor microenvironment through a combination of direct and indirect e…

…late the etiology by which irAEs are initiated in patients with cancer, we utilized a unique series of syngeneic, transplantable tumor…

…sions In situ spatial proteomic and RNA analysis of a secondary sarcoma post cell therapy treatment support the finding that the second…

…trating Lymphocyte (TIL) therapy is an autologous treatment for solid tumors involving isolation and ex vivo expansion of polyclonal T lymph…

…of IT PH-762 in cutaneous squamous cell carcinoma, melanoma, or Merkel cell carcinoma, to determine the pharmacokinetic profile of PH-762 after IT in…