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…-0335 Figure 2. Immune checkpoint expression on γδ T cells from pancreatic ductal adenocarcinoma single-cell RNA sequencing datasets). In addition, γδ T cells e…

…e include adult participants, aged ≥18 years, in three cohorts: pancreatic ductal adenocarcinoma; benign pancreatic controls (chronic pancreatitis or new-onset …

…demonstrate that tumour cell-autonomous expression of SMPD1, in pancreatic ductal adenocarcinoma (PDAC), is associated with poorer patients’ outcomes. Smpd1 abl…

… KM curve represents a distinct clinical or molecular subgroup. CRC, colorectal cancer; CXCR4, CXC-chemokine receptor 4; KM, Kaplan…

…nocarcinoma (PDAC, 90–95%), non-small cell lung cancer (30%) or colorectal cancer (40%).1 The prognosis is particularly bad in the case of pancre…

…apy has been tested in other solid tumour malignancies, such as renal cell carcinoma (29% ORR in 7 patients),49 non-small cell lung cancer (23% ORR …

…0.01). Because CA19-9 is an established prognostic indicator in PDAC, this imbalance represents a source of residual confounding tha…

…oenvironment (TME) that contribute directly to the lethality of pancreatic ductal adenocarcinoma (PDAC), but their potential interactions have not been explored…

…r cytologic classification of SPLs). The target categories were pancreatic ductal adenocarcinoma (PDAC), pancreatic neuroendocrine tumor/carcinoma (PNET/C), and…

…asing detection of small, incidental pancreatic lesions—such as pancreatic neuroendocrine tumours (pNETs) and cystic lesions—creates a growing management dilemma…

…igure 1Overall and sex-stratified Pancreatic adenocarcinoma and Type 2 Diabetes mellitus-related age-adjusted mortality rates per 1,000,000 in the United States…

…Introduction Pancreatic steatosis is increasingly recognized as a precursor to metabolic dysfunct…