Entity family
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This disease is selected. Its supporting articles are shown below.
…assessment characterizing the immunopeptidome of 10 HNSCC and 3 NSCLC cell lines derived from 9 different patients, revealed 74,578 u…
…e remain key challenges that limit the therapeutic potential in solid tumors. T cells are hardwired to pursue a natural path of differentiat…
…Background The application of T and NK-cell therapies to solid tumors remains a challenge due to the limited repertoire of suitable t…
… responses.Methods Bria-OTS+ cell lines targeting lung, breast, melanoma, and prostate cancers were genetically engineered to express im…
…at TAA-T products targeting preferentially expressed antigen in melanoma (PRAME) can be transduced with a TGFbRII dominant negative rece…
…juvant IO alone in macroscopic Stage III or resectable Stage IV melanoma. However, the optimal peri-operative strategy, including IO reg…
… potential in hematologic malignancies and melanoma, but not in epithelial cancers, the most common malignancy type. Here, we report ongoing compl…
…a key mediator of clinical responses in metastatic melanoma and gastrointestinal cancers. 1 2 However, the baseline molecular features defining neoantig…
…last decade for a range of malignancies, including melanoma and non-small cell lung cancer. 1 While effective, these agents are frequently associated with…
…es, activity in rGBM has been disappointing. Emerging data from melanoma, lung, and renal cancers suggest that treatment-induced or dise…
…eckpoint inhibition (ICI) has led to improved response rates in metastatic cancer, however only a subset of patients respond. The exact reason(s)…
…ts. However, their use remains largely confined to melanoma and NSCLC due to systemic Treg depletion and related peripheral toxicity.…