Browse diseases

…able for treating active systemic lupus erythematosus (SLE) and lupus nephritis (LN). However, GC can cause significant comorbidities and irrev…

…ertiary centre (UCLH).Methods A retrospective analysis included SLE patients treated with belimumab (n=25), obinutuzumab (n=8), and…

…ith expectations for this patient population (table 1). Besides COVID-19, the most common SIs were pneumonia, urinary tract infections a…

… type II anti-CD20 monoclonal antibody, has proved effective in lupus nephritis (LN) in randomized clinical trials, when adding to standard the…

…an inactivated vaccines in SLE patients. Factors such as active lupus nephritis and moderate-to-high dose corticosteroid use appeared to be ass…

…l activity in SLE, with a focus on lupus nephritis (LN).Methods SLE serum consistently induces neutrophil clustering during NET for…

…Objectives Anti-dsDNA IgG antibodies are characteristic for systemic lupus erythematosus (SLE). Evidence suggests that these antibodies contribute to va…

…logic evaluation of renal tissue is pivotal in the diagnosis of lupus nephritis (LN) since flares contribute to poor outcomes. Nonetheless, mol…

… inflammation despite immunosuppression drives kidney damage in lupus nephritis (LN). Current guidelines rely on proteinuria to assess response…

…Objectives Lupus nephritis (LN) is more common in Black than in White ethnic groups. High …

…ete renal response (CRR) at Week 76 (W76) in adults with active lupus nephritis (LN). These exploratory analyses aimed to evaluate histological…

…G318 to treat refractory systemic lupus erythematosus (SLE) and lupus nephritis (LN) in a phase I clinical trial. We report up to 67-month foll…