…eveal that the LTO1/YAE1 complex is frequently overexpressed in human cancers, where it negatively regulates MHC-I. Moreover, low doses of ir…
human cancers
This disease is selected. Its supporting articles are shown below.
Articles mentioning human cancers
11 articles · page 1 of 1…oclonal antibodies against DKK1 peptide-HLA-A2 complex to treat human cancers. J Immunother Cancer 2024;121:e008145. doi: 10.1136/jitc-2023–0…
…otoxic activity (CD4+CTLs) have been reported in the context of viral infections, autoimmune disorders, and more recently in patients with vario…
… vaccines based on shared mutated NeoAgs might be developed for COAD, STAD and UCEC cancers, with a global coverage, and for PAAD an…
…specific antibody, as monotherapy in patients with antigen-rich solid tumors resistant to anti-PD(L)1: Journal for ImmunoTherapy of Cancer. …
…dentify additional genetic regulators of CAR-T cell activity in solid tumors.Ethics Approval The animal work described in this abstract was …
…only underlie resistance to immune checkpoint blockade (ICB) in solid malignancies. Novel combination therapies may overcome these barriers, provi…
…AR0602 in combination with HDAC inhibitors for the treatment of solid malignancies including those resistant to current ICB therapies.…
…Background Macrophages pervade solid tumors where they predominantly contribute to tumor progression but al…
…Background Mutant forms of p53 are present in most human cancers, but targeting these proteins remains a major challenge. The re…
…s differences between human and rodent immunobiology. Moreover, human cancers progressively develop in nature over long periods, while precli…