epithelial cancershematologic malignancieschimeric antigen receptor (CAR) T-cell therapy
…d the treatment of hematologic malignancies, its application to epithelial cancers remains limited by unpredictable toxicities. Insights from CD19…
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35disease mentions
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hematologic malignancies
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Articles mentioning hematologic malignancies
34 articles · page 3 of 3hematologic malignanciesChimeric antigen receptor (CAR) T cell therapy
… receptor (CAR) T cell therapy has revolutionized treatment for hematologic malignancies, but response rates vary significantly among patients, even whe…
ccRCChematologic malignanciesIB-T101OUTLAST™ conditioningTongji Hospital Medical Ethics CommitteeID TJ-IRB202412051-1
…ad to superior clinical outcomes for IB-T101 CAR-T cells in the ccRCC solid tumor setting.Methods Here we report an in-progress phase…
solid tumorshematologic malignanciesgraft-vs-host diseaseA2B395A2B530A2 BioBASECAMP-1
…y targeting epidermal growth factor receptor (EGFR) in advanced solid tumors with human leukocyte antigen (HLA) loss of heterozygosity (LOH)…
melanomaadvanced solid cancershematologic malignanciesIcahn School of Medicine at Mount SinaiChimeric Antigen Receptor (CAR) T cell therapyCAR T cell therapyTumor irradiation
…c murine models of extensive metastatic lung adenocarcinoma and melanoma to evaluate CAR T cell therapy following tumor irradiation. CAR…
solid tumorshematologic malignanciesmetastatic urothelial carcinomamUCRNDO-564
…ies have shown success in hematologic malignancies, efficacy in solid tumors has been limited, partly due to T-cell exhaustion within the im…
Acute Myeloid Leukemiasolid tumorsOvarian Cancerhematologic malignanciesAMLUniversity of MinnesotaTriKE
…systems we currently employ. To address this issue we generated Acute Myeloid Leukemia (AML) and Ovarian Cancer (OC) models using three different mous…
hematologic malignanciessolid tumorsChimeric Antigen Receptor T (CAR-T) cell therapy
…erged as an advanced and highly effective approach for treating hematologic malignancies with its scope rapidly expanding to encompass diverse applicati…
solid tumorshematologic malignanciesVEGFChimeric antigen receptor (CAR)-T cell therapy
…l with metabolic enhancement to improve therapeutic efficacy in solid tumors.Methods To overcome these barriers, we developed a next-generat…
hematologic malignanciessolid tumorsimmune checkpoint inhibitorsImmuno-oncologyT cell therapiesin vivo gene editing
…ibitors and T cell therapies have mediated durable responses in hematologic malignancies and select solid tumors, most patients still relapse or fail to…