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12disease mentions

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dMMR

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Articles mentioning dMMR

5 articles · page 1 of 1

4CPS-301 Efficacy of combination of anti-PD-1/l1 agents with chemotherapy in advanced or recurrent endometrial cancer with deficient mismatch repair: an indirect treatment comparison

ejhpharm · abstract · 2026-03-18 · 4 matching annotations

86.2%

dMMR endometrial cancer EC pembrolizumab Durvalumab dostarlimab

…tic alternatives (ETAs) for patients with advanced or recurrent dMMR EC, through an adjusted indirect treatment comparison (ITC).Mat…

Memory B cell subset shapes antitumor immunity and response to PD-1 blockade in mismatch repair-deficient colorectal cancers

jitc · abstract · 2026-01-08 · 3 matching annotations

87.1%

dMMR dMMR CRCs CRC colorectal cancer CCL19 anti-PD-1 treatment TCGA The Cancer Genome Atlas

… show that CCL19 generated by STING/type I IFN/STAT1 pathway in dMMR/MSI-H CRC cells can promote the expansion of memory B cells, wh…

IDDF2026-ABS-0310 The dynamics of serum protein and their potential for predicting therapeutic efficacy in patients with non-metastatic mismatch repair-deficient and microsatellite instability-high colorectal cancer receiving PD-1 checkpoint inhibitors

gutjnl · abstract · 2026-06-26 · 2 matching annotations

77.0%

CRC dMMR PD-1 checkpoint inhibitors immunotherapy

…study demonstrated that nearly 70% of non-metastatic dMMR/MSI-H CRC patients achieved CR following PD-1 inhibitor therapy. Specific…

Deficient mismatch repair/microsatellite instability-high colorectal cancer: current treatment paradigms, limitations and future perspectives

bmjonc · abstract · 2026-02-15 · 2 matching annotations

87.6%

dMMR colorectal cancer CRC Neoadjuvant immunotherapy cytotoxic chemotherapy Food and Drug Administration

…ic Food and Drug Administration approval in 2017 for metastatic dMMR/MSI-H solid tumours. Recent evidence also supports the benefit …

Deep learning predicts microsatellite instability status in colorectal carcinoma in an ethnically heterogeneous population in South Africa

jclinpath · abstract · 2025-12-15 · 1 matching annotations

79.0%

CRC colorectal carcinoma dMMR

… of patients from South Africa.Methods Our cohort comprised 197 CRC resection specimens, with scanned whole slide images tessellate…