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…rs targeting CD70 show early promising results for their use in RCC in preclinical and clinical trials. However, further research a…

…Background Clear cell renal cell carcinoma (ccRCC) is the most common and lethal form of kidney cancer. Despite th…

… analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma. The Journal of Pathology. 2007;213(4):392–401.Su C, Lv Y, Lu W…

…as 23.3 for ccRCC (kidney), 1.9 for DLBCL (spleen), and 3.6 for MESO (lung). In comparative analyses, CD70 expression in ccRCC was s…

…esponse to ICIs (p=0.7) (figure 1E). In patients with localized ccRCC undergoing nephrectomy, circulating plasma GDF-15 levels decrea…

…al of 34 patients with intermediate-high or high-risk localized ccRCC were included. Tumor somatic mutation profiling targeting 12 li…

…l cancers including clear cell renal cell carcinoma (ccRCC) and soft tissue sarcoma (STS). 1 2 Yet, many TLS-positive tumors remain resistant, sugg…

…ad to superior clinical outcomes for IB-T101 CAR-T cells in the ccRCC solid tumor setting.Methods Here we report an in-progress phase…

…ed to assess the feasibility and efficacy of TIL expansion from clear cell renal cell carcinoma (ccRCC) to enhance TIL-based ACT. Given the significant role of hypoxia…

…n-human phase I trial targeting an ERV-derived tumor antigen in ccRCC demonstrated the safety and preliminary efficacy of adoptively …

…mentation analysis of selected phenotypes (B). ROI from Stage 3 ccRCC containing TLSs (Panel A and B, white box). The single-cell seg…

… clear cell renal cell carcinoma (ccRCC) remains suboptimal. In ccRCC, an increased infiltration of CD8 + T cells does not necessaril…