Browse diseases

…er cell line and primary human innate immune cells. We used the MC38 colorectal cancer and the highly immunosuppressive B16F10 melanoma mouse models t…

…targeting this program may provide a means of enhancing certain cancer immunotherapies. These neutrophils could further invoke both (n…

… immunosuppression provides key insights into several facets of cancer research and therapy. If single-cell detection of cytokines spa…

…slational research. To ensure seamless integration into diverse cancer drug development pipelines, MHC MACSimer reagents feature the f…

…t after adjusting for correlates of advanced disease, including cancer stage and metastatic burden. Notably, we present evidence that …

…Background Despite recent advances, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, part…

… V12.6) to obtain expression data of the β6 integrin across The Cancer Genome Atlas (TCGA).Results High expression of β6 integrin mRNA…

…he discovery of novel epitopes and the development of effective cancer immunotherapies targeting HLA-A2.1-restricted antigens.…

…more effective and scalable NK cell-based treatment options for cancer patients.…

…cell function in obesity and aging are not fully understood. In cancer, CD8+ T cells become terminally exhausted, a differentiation st…

…ult and pediatric solid tumors including neuroblastoma, glioma, melanoma and sarcoma.Acknowledgements This work was supported by researc…

…nds Immunol. 2015;36(4):265–276.Chen DS, Mellman I. Elements of cancer immunity and the cancer-immune set point. Nature. 2017;541(7637…