…e phenotyping, and DC sorting. DCs from primary and ACT escaped tumors were assessed for T cell activation function and subjected for …
Tumors
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Articles mentioning Tumors
25 articles · page 1 of 31236 Tumor antigen-specific T cells increase tertiary lymphoid structure response in murine melanoma
…. We are currently testing whether expanded Tfh TCR clones from tumors are tumor-reactive, and whether they can be mapped in a spatial…
…e demonstrated limited efficacy and significant side effects in solid tumors, primarily due to the expression of CD47 on healthy cells such …
…nal type I dendritic cells (cDC1), CD8 T cells, and NK cells in tumors. This loss of a tumor-reactive phenotype was mechanistically li…
…loit inducible genetic systems to activate the immune system in tumors in a safe and spatiotemporally regulated manner. While lentivir…
…u) pre-conditioning, IL-12 GEMys cure mice of established solid tumors and provide protection from subsequent rechallenge with the sam…
…bsequently tumor immunity. In this study we used the transgenic melanoma mouse model tg(Grm1)EPv, which spontaneously develops melanoma …
… therapy promotes the emergence of new T cell clonotypes within tumors, suggesting de novo priming in the periphery. Yet, the mechanis…
…e tissue-specific and has been correlated with inflammation and tumors. Among HERVs, the HERV-K family is made up of 10 groups (HML-1 …
…ler-like receptors positions them as powerful effector cells in tumors that evade classical immune escape mechanisms. Furthermore, dis…