Browse diseases

…arce reports about the relationship between IL-20 subfamily and systemic sclerosis (SSc). Here, we evaluated the serum level of IL-20 subfamily cytokine…

…ellular matrix (ECM) accumulation causing organ dysfunction. In SSc, ECM production is thought to be initiated by inflammatory trig…

…ity. We aimed to investigate serum BRD4 levels in patients with systemic sclerosis (SSc) and its association with disease characteristics.Material and M…

…Caveolin-1 (CAV1) are known drivers of fibroblast activation in Systemic sclerosis (SSc). We recently reported that reduction in primary cilium (PC) len…

…nts of type I interferon (IFN-I) that have been associated with systemic sclerosis (SSc). They infiltrate affected tissues, drive overproduction of IFN-…

…t in U3RNP/Ku groups, and unique metabolic signaling related to pulmonary arterial hypertension in Th/To+ cases.Conclusions This study provides the first multi…

… onset, she presented with Raynaud’s phenomenon, sclerodactyly, gastroesophageal reflux disease and exertional dyspnea. High-resolution imaging of the lungs re…

…diac involvement is a major cause of morbidity and mortality in systemic sclerosis (SSc). Autoantibodies may help identify patients at increased cardiov…

…stic studies and therapeutic testing. Ongoing work with excised calcinosis samples, analysed by immunochemistry, will further link macroph…

…Introduction Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by autoantibodies…

…ic background may influence the development and the severity of systemic sclerosis (SSc). Available SSc mouse models do not mimic the full spectrum of S…

…a for SSc were enrolled; patients with coronary artery disease, pulmonary arterial hypertension and other cardiomyopathies were excluded. Demographic and clini…