…ferating B and T-cells, suggesting potential effector function. Melanoma-BM LAs also had increased intratumoral CD8+T-cells, unlike LUAD-BM…
Solid tumors
This disease is selected. Its supporting articles are shown below.
Articles mentioning Solid tumors
190 articles · page 6 of 16…an phase 1 clinical trial of superficially accessible, advanced solid tumors. Herein, we report pharmacokinetic (PK), anti-drug antibody (AD…
…ss low immune permissive tumor states in patients with advanced solid tumors.Trial Registration NCT03217747Acknowledgements The study was fi…
…3-CAR-NK cells resulted in potent antitumor activity in vivo. 1 Multiple myeloma is a plasma cell cancer that develops in the bone marrow and re…
…Background Solid tumors present a major challenge to CAR-T therapy due to antigen heter…
… that has shown promising clinical efficacy, especially against hematological cancer, with multiple FDA-approved therapies. Current autologous CART …
…provides a basis for the improvement of immunotherapies against solid tumors by manipulating DNA repair.References Wherry EJ, Kurachi M. Mol…
…R-T cells plus amplifying RNA vaccine in relapsed or refractory solid tumors: the phase 1 BNT211-01 trial. Nat Med. 2023;29:2844–2853.Hambur…
…dentify additional genetic regulators of CAR-T cell activity in solid tumors.Ethics Approval The animal work described in this abstract was …
…Background The efficacy of CAR-T cells against solid tumors is limited by the suppressive tumor microenvironment and T cell…
…on was implemented. Two clinical development programs targeting solid tumors are currently underway. These CAR constructs will be integrated…
…olytic virus (OV) therapies face limited efficacy alone against solid tumors. We have shown that combining CAR T cell and VSV (vesicular sto…