Entity family
Named diseases, disorders, syndromes, injuries, and health conditions. Examples include epilepsy, diabetes, stroke.
This disease is selected. Its supporting articles are shown below.
… cancer treatment but faces significant challenges in targeting solid tumors. The epigenetically programmed exhaustion poses a key challenge…
…ion marker in CD276-redirected CAR T cells for the treatment of solid tumors. Journal for Immunotherapy of Cancer 2024;12(Suppl 2):A389. doi…
…buting to the development of more effective immunotherapies for solid tumours.This work was supported by the European Research Council (ERC) …
…xpanded NK cells combined with NKTR-255 and dinutuximab against OSA in vitro and in vivo. NK cells in combination with immune modul…
…Background TK-6302 is a novel TCR-T cell therapy targeting PRAME, designed with best-in-class potential. It incorporates a high-…
…cells (TCR-T cell) represents a promising strategy for treating solid tumors by redirecting autologous T cells to recognize tumor-specific n…
…u) pre-conditioning, IL-12 GEMys cure mice of established solid tumors and provide protection from subsequent rechallenge with the sam…
…cers once considered untreatable. However, its effectiveness in solid tumors is often limited by multifactorial T cell dysfunction, particul…
… and had gradually acquired an effector-memory phenotype. Human melanoma TIL showed robust CAR expression (>80%) following transduction,…
…the tumor stroma. These challenges are especially pronounced in cold tumors characterized by low immune infiltration, restricting the broad…
…ollowing CAR-T therapy in patients with leukemia, lymphoma, and myeloma.Methods MEDLINE, Embase, Web of Science, and Cochrane CENTRAL d…
…d Treatments that yield deep and durable responses against many solid tumors remain lacking. CAR T cell therapy is promising but is hindered…