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…fferentiation downstream of TLR7/8/9 signaling, contributing to systemic lupus erythematosus (SLE) pathogenesis. Despite its genetic and pre-clinical valida…

…to standard therapy, and reinforce the role of BEL in long-term SLE management.Funding GSK…

…treatment responses, and safety of anifrolumab in patients with systemic lupus erythematosus (SLE).Methods We are reporting the clinical profiles, treatment…

…Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving dysregulated in…

… approximately 80% after standard induction, with elderly-onset SLE and advanced CKD associated with poorer outcomes. Importantly, …

…Objectives Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with variable clinical …

…tives Glucocorticoids (GCs) have been used for the treatment of systemic lupus erythematosus (SLE) for over 60 years. Current recommendations advocate for t…

…erns on health-related quality of life (HRQoL) in patients with systemic lupus erythematosus (SLE) and to identify specific damage patterns affecting physic…

…l activity in SLE, with a focus on lupus nephritis (LN).Methods SLE serum consistently induces neutrophil clustering during NET for…

…ing that steroid-free remission is a realistic clinical goal in SLE management. Steroid-free management of more inflammatory manife…

…and recurrent infections.Methods A 45-year-old woman with known SLE (ANA/dsDNA-positive, hypocomplementaemic) previously manifestin…

…cally in hyperlipidemic lupus mice following mPSL pulse.Methods SLE was induced using the TLR7 agonist imiquimod (IMQ) in C.KOR/Stm…