Browse diseases

…shment.Methods Retrospective cohort of 347 patients with active SLE receiving treatment intensification at inclusion. Comorbidities…

…Objectives The disease activity assessment of systemic lupus erythematosus (SLE) mainly relies on the SLEDAI score, but its evaluation ind…

…hogenicity of antibody responses. GWAS surveys of subjects with Systemic Lupus Erythematosus (SLE) associate TNFRSF13B with risk but the high TNFRSF13B poly…

…s potent and sustained B-cell depletion, is approved for active lupus nephritis. The Phase III, multicenter, randomized, double-blind, placebo-…

…ating rearrangement of transcriptional coordination.Conclusions SLE monocytes exhibit widespread transcriptional changes. These fin…

…mpact of antiphospholipid antibodies (aPLs) on the evolution of systemic lupus erythematosus (SLE) disease manifestations other than thrombosis and pregnanc…

…ip with organ damage and NRLConclusions Low vitamin D levels in SLE were independently linked to higher NLR and greater organ damag…

…s, or depression.Conclusions Sleep disturbances are frequent in SLE patients, mainly associated with nighttime pain, stress, and de…

…t, organ involvement, immunological findings and comorbidities. SLE disease activity was measured using SLEDAI 2K (Systemic Lupus E…

…ed antibodies (DMa Ab) were detected in 9 (17.6%) patients with SLE: only ZnT8 Ab in 4 (7.8%), only GAD Ab in 4 (7.8%) women, and Z…

… staining (CD19+ CD27++) was also observed in PBMCs from active SLE patients. Pre-blocking experiments with unconjugated 100-bp dsD…

…Objectives Cardiovascular disease is a leading cause of morbidity and mortality in systemic lupus…