PFICALGSAlagille syndromeProgressive familial intrahepatic cholestasis
…ubin levels).Six patients were on odevixibat. Four patients had PFIC (2 BSEP mutations, 1 MDR3 deficiency, and 1 FIC1 deficiency) an…
5articles mentioning diseases
14disease mentions
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PFIC
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Articles mentioning PFIC
5 articles · page 1 of 1Alagille syndromealpha1-antitrypsin deficiencylow phospholipid-associated cholelithiasisintrahepatic cholestasis of pregnancybenign recurrent intrahepatic cholestasisPFICIBATiursodeoxycholic acidintestinal bile acid transporter inhibitors
…cause PFIC types 1–3. Several other congenital diseases such as Alagille syndrome and alpha1-antitrypsin deficiency comprise cholestatic pruritus…
PBCintrahepatic cholestasisMDR3 deficiencyprimary biliary cholangitis (PBC)cholestatic liver diseasePFICbiliary fibrosischronic liver injuryPSCprimary sclerosing cholangitis (PSC)+3 more
…ho have severe loss-of-function ABCB4 mutations and PSC but not PBC. Mdr2-/- mice appear to respond to modulation of other bile aci…
Progressive Familial Intrahepatic Cholestasis (PFIC)PFICMaralixibatMRXEUMRX-MRX
…le acid transporter, is approved in the EU for the treatment of Progressive Familial Intrahepatic Cholestasis (PFIC) in individuals ≥3 months of age. In the 26-week placebo-control…