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…s, or clinical determination by the investigator. Patients with cirrhosis were identified as having signs of PHT at baseline if they had …

…Imbalances were also seen in the underlying medical history for osteoporosis (elafibranor, 19.4%; placebo, 3.8%) and osteopenia (elafibranor…

… high-risk patients (stratified according to biochemistry) with primary biliary cholangitis (PBC) is well-established. An inadequate response to 1st-line t…

…Background Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease marked by progress…

…, have been inconsistently reported and poorly characterized in systemic sclerosis (SSc). AMA mainly target E2-pyruvate dehydrogenase complex (E2-PDC).M…

…Introduction Primary biliary cholangitis (PBC) is a rare chronic cholestatic disease that despite current ther…

…Primary biliary cholangitis (PBC) is a chronic, progressive autoimmune liver disease, chara…

…osis and key biochemical markers remain stable in patients with PBC, including those with advanced stage disease.…

…tion which, left untreated or inadequately treated, can lead to cirrhosis, transplantation or death. Approximately 40% of patients do not…

…ding autoimmune thyroiditis (10.5%), pernicious anemia (10.5%), Sjögren’s syndrome (5.3%), and systemic sclerosis (5.3%).Biological tests revealed…

…Treatment goals of Primary biliary cholangitis (PBC) are to prevent end stage liver disease and to manage dise…

…eiving seladelpar as monotherapy in these studies.Patients with PBC who had an inadequate response or intolerance to UDCA, ALP ≥1.6…