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… found an association between NPSLE and SLEDAI-2K and SLICC DI (SLE International Collaborating Clinics Damage Index) score.Conclus…

…nostic metrics.Results Among 85 patients, 25 were classified as NPSLE, 39 as SN-SLE and 21 as NP-non-AI. NPSLE patients were younger,…

…est diagnostic performance (AUC=0.94).Conclusions Patients with NPSLE and non-NPSLE showed distinct TSPO uptake in brain lesions, ind…

…ry subtypes. CP volume is significantly higher in patients with SLE than in HCs (L: F=22.273, p<0.001; R: F=21.176, p<0.001). ROC a…

… findings suggest OBZ may induce superior clinical responses in NPSLE through enhanced B cell depletion, with acceptable safety at 12…

… 28.7 ± 6.9 years and mean disease duration of 7.6 ± 3.8 years. NPSLE was classified according to ACR criteria. Clinical and serologi…

…(CNS) and peripheral nervous system (PNS)—based on the 1999 ACR NPSLE case definitions and current literature. Statistical analyses w…

…ainst NPSLE. Additional action is required in the management of SLE patients with high disease activity and self-reported cognitive…

…s (adjusted p<0.05).Conclusions Neuropsychiatric involvement in SLE increases clinical manifestations and extends organ damage beyo…